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OCTAFLUOROCYCLOPENTENE
| Flammability | 1 | |
| Toxicity | 4 | |
| Body Contact | 2 | |
| Reactivity | 2 | |
| Chronic | 2 | |
| SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 | ||
Used for cleaning, degreasing electrical equipment and electronics
C5-H8, "cyclopentene, octafluoro-", perfluorocyclopentene, "1, 2, 3, 3, 4, 4, 5, 5-
octafluorocyclopentene", "1, 2, 3, 3, 4, 4, 5, 5-octafluorocyclopentene"
May form explosive peroxides.
Harmful by inhalation.
Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre- existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern. Considered an unlikely route of entry in commercial/industrial environments. Ingestion may result in nausea, pain, vomiting. Vomit entering the lungs by aspiration may cause potentially lethal chemical pneumonitis.
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn). The material may produce moderate eye irritation leading to inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis.
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Fluorocarbons remove natural oils from the skin, causing irritation,dryness and sensitivity.
The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress. Material is highly volatile and may quickly form a concentrated atmosphere in confined or unventilated areas. Vapor is heavier than air and may displace and replace air in breathing zone, acting as a simple asphyxiant. This may happen with little warning of overexposure. Depression of the central nervous system is the most outstanding effect of most halogenated aliphatic hydrocarbons. Inebriation and excitation, passing into narcosis, is a typical reaction. In severe acute exposures there is always a danger of death from respiratory failure or cardiac arrest due to a tendency to make the heart more susceptible to catecholamines (adrenalin). Acute intoxication by halogenated aliphatic hydrocarbons appears to take place over two stages. Signs of a reversible narcosis are evident in the first stage and in the second stage signs of injury to organs may become evident, a single organ alone is (almost) never involved. Exposure to fluorocarbons can produce non-specific flu-like symptoms such as chills, fever, weakness, muscle pain, headache, chest discomfort, sore throat and dry cough with rapid recovery. High concentrations can cause irregular heartbeats and a stepwise reduction in lung capacity. Heart rate may be reduced.
Principal routes of exposure are usually by inhalation of vapor and skin contact/absorption. Prolonged or continuous skin contact with the liquid may cause defatting with drying, cracking, irritation and dermatitis following. Administration of 1,2,3,3,4,4,5,5-octafluoeocyclopentene to the pregnant rat for 6 hours a day between days 6 and 19 post coitum produced evidence of maternal toxicity at 100 ppm and a marginal effect on lung and body weight at 10 and 30 ppm. With respect to the conceptus, a slight reduction in mean foetal weight at 100 ppm was accompanied by a slightly increased incidence of major cardiovascular malformations that was of equivocal biological significance, but not by any other evidence of disturbance to development. Fluorocarbons can cause an increased risk of cancer, spontaneous abortionand birth defects.
