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Bacterial argonaute sets sail
Sheilagh Molloy
In eukaryotes, argonaute proteins have important roles in small RNA-mediated gene silencing. In a recent issue of Molecular Cell, Alexei Aravin and colleagues demonstrate a role for a bacterial argonaute protein in silencing foreign nucleic acids.
Argonaute proteins have been identified in a range of bacteria and archaea. Although several crystallographic structures have been made available…