西亞試劑：A Metabolic Sensor Governing Cell Size in Bacteria

A Metabolic Sensor Governing Cell Size in Bacteria

Richard B. Weart,1 Amy H. Lee,1 An-Chun Chien,1 Daniel P. Haeusser,1 Norbert S. Hill,1 and Petra Anne Levin1,

1 Department of Biology, Washington University, St. Louis, MO 63130, USA

Corresponding author
Petra Anne Levin
Summary

Nutrient availability is one of the strongest determinants of cell size. When grown in rich media, single-celled organisms such as yeast and bacteria can be up to twice the size of their slow-growing counterparts. The ability to modulate size in a nutrient-dependent manner requires cells to: (1) detect when they have reached the appropriate mass for a given growth rate and (2) transmit this information to the division apparatus. We report the identification of a metabolic sensor that couples nutritional availability to division in Bacillus subtilis. A key component of this sensor is an effector, UgtP, which localizes to the division site in a nutrient-dependent manner and inhibits assembly of the tubulin-like cell division protein FtsZ. This sensor serves to maintain a constant ratio of FtsZ rings to cell length regardless of growth rate and ensures that cells reach the appropriate mass and complete chromosome segregation prior to cytokinesis.

• 以上資料由西亞試劑：http://hendrickstechnology.com/ 提供此產(chǎn)品的詳細(xì)信息如密度,含量,分子式,分子量等均可在西亞官網(wǎng)查詢   
• 相關(guān)產(chǎn)品如溴化汞硝酸亞汞氯化亞汞乙酸苯汞氯化鉀汞 碘化汞鉀硫氰酸汞硫酸亞汞氧化汞氯化汞碘化汞硝酸汞三氯氧磷三氯化磷碘甲烷二碘甲烷三碘甲烷三氟碘甲烷氘代碘甲烷碘乙烷1,2-二碘乙烷甲酸銣碘化銣溴化銣鉻酸銣硫酸銣氟化銣硝酸銣氯化銣碳酸銣硫酸鐿 碳酸鐿氯化鐿硝酸鐿氧化鐿等均有銷售.歡迎訂購(gòu)