西亞試劑：Influenza A Virus PB1-F2: A Small Protein with a Big Punch

Influenza A Virus PB1-F2: A Small Protein with a Big Punch

Gina M. Conenello1 and Peter Palese1,2,

1 Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA
2 Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA

Corresponding author
Peter Palese
Virulence factors, such as the recently discovered PB1-F2, contribute to the pathogenesis and comorbidity of influenza A virus. In this issue of Cell Host & Microbe, McAuley et al. characterize the role of PB1-F2, including in the pandemic 1918 virus, in causing increased lung pathology and fatal pneumococcus infection in mice. This work sheds light on the mechanisms of pathogenicity during influenza A virus infections.

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